The upper chambers of the heart (the atria) beat irregular (quiver) and mostly fast instead of beating effectively to move blood into the ventricles. This condition is associated with a higher risk for cardiac blood clots, stroke, heart failure and other heart-related complications. About 10 % - 20 % of patients who suffer from an ischemic stroke also suffer from atrial fibrillation.
Premature Contraction Detection (PC)
Extra, abnormal heartbeats generated in abnormal locations of your heart, either in the atria (PAC) or in the ventricles (PVC) or the cardiac conduction nodes (PNC). These extra beats disrupt your regular heart rhythm, sometimes causing palpitations (e.g. skipped beats) in your chest. It may occur singularly or repetitively with various incidence. If not stress-related, they are a sensitive marker for a multitude of cardiac disorders, elevated ischemic stroke risk with PC.
Fast heart rate of more than 100 beats per minute (BPM) in adults. Unless being caused by physical or mental stress, indicator for cardiac and extra-cardiac disorders (e.g. coronary heart disease, hyperthyroidism, fever).
Slow heart rate, heart rate of less than 55 beats per minute in adults. Unless caused by endurance training heart adaption, bradycardia may be related to a multitude of cardiac and extra cardiac disorders (e.g. electrolyte imbalance, medication, coronary and / or valvular heart disease).
The sensitivity and the specificity of PARR technology are concluded by comparing the detection results of PARR algorithm to the medical reference of the ECG.
PARR Technology has a sensitivity of 74.07% regarding PC and 78.67% regarding AFib. This result is obtained from clinical patients and cardiologic patients without data selections. Considering the amount of waveforms with high complexity among the raw data entries, sensitivity over 70 % is considered extraordinary. Over 90 % or even 100 % sensitivity might be possible with pre-test patient selection.
There are 2 types of stroke, ischemic type and hemorrhagic type. Ischemic strokes represent about 85% while hemorrhagic types concern about 15% of all cases.
Among ischemic type stroke, 70% is caused by embolization.
About 10-20% of patients who suffer from an ischemic stroke have AFib.
Coronary Heart Disease
On the surface of the heart, coronary arteries are present. The lack of coronary perfusion is a major cardiac disease for people over 40 years old. (fig. A)
A clogged coronary artery leads to a lack of oxygen in the ventricle peripheral to the arterial supply area. This may establish a pathological pacemaker which irregularly triggers contractions. (fig. B)
Premature ventricular contractions (PVCs) may indicate the presence of coronary heart disease. (fig.C)